A Review on Complication of Diabetes Mellitus and Its Therapy

Diabetes is a grouping of anatomic and chemical problems resulting from a number of factors in which an absolute or relative deficiency of insulin and/or its function is present. It tends to run in Families; is associated with accelerated atherosclerosis, and predisposes to certain specific microvascular abnormalities including retinopathy, nephropathy and neuropathy. There are other problems, such as the lessening of resistance to infection, especially if the diabetes is poorly controlled. The objective of the present review is to provide an epidemological, Experimental (alloxan, streptozotocin and other Drug induced diabetes) and available therapy; Insulin and other oral hypoglycemic Drugs generally used for therapy of diabetes have side effects. The review contains hyperglycemia increases reactive oxygen species (ROS) production and its effect. The review also contains Herbal plants which have been reported as antidiabetic, antioxidant and antihyperlipidemic activity. This review will also be helpful to researchers for understanding better possibilities about development of Alternative methods.